The Foaming Window – A New Concept and Mechanism for Biocomposite Foams Processing by Two-Step Sintering
Keywords:Biocomposite foams, two-steps sintering, nanostructure, foaming reactions.
The two steps sintering process provide economical, technological and innovative advantageous aspects to produce biocomposite foams for alloplastic bone grafts applications. The kinetic window mechanism, working during the 2nd TSS step, provides the nanostructured ceramic matrix, respectively improved biocompatibility. Simultaneously, the high porous structure, fitting the trabecular bone tissue, remained an important technical request of such applications up to this research. The porous biocomposite scaffold could be designed using specific foaming agents, like titanium hydride, calcium carbonate and ammonium bicarbonate, by controlling the foaming reactions depending on the foaming agents’ type and content into the chemical composition of the initial biocomposite powder mixture. The new concept of foaming window, working during the 1st TSS step, includes these factors able to provide the specific foam structure fitting the required biocomposite foams porosity. Both windows may work for the benefit of the nanostructured highly porous biocomposite manufacturing by TSS process, in advantageous technical and economical terms.
Chen IW and Wang XH. Sintering dense nanocrystalline ceramics without final-stage grain growth. Nature 2000; 404:168-71. https://doi.org/10.1038/35004548
Wang X, Deng X, Bai H, Zhou H, Qu W, Li L, et al. Two-step sintering of ceramics with constant grain-size, II: BaTiO3and Ni–Cu–Zn Ferrite, J Am Ceram Soc 2006; 89(2): 438-43. https://doi.org/10.1111/j.1551-2916.2005.00728.x
Wright GJ and Yeomans JA. Constrained sintering of yttriastabilized zirconia electrolytes: The influence of two-step sintering profiles on microstructure and gas permeance. International Journal of Applied Ceramic Technologies 2008; 5(6): 589-96. https://doi.org/10.1111/j.1744-7402.2008.02263.x
Ruys AJ, Gingu O, Sima G and Maleksaeedi S. Powder processing of bulk components in manufacturing. In: Nee AYC, Ed. Handbook of Manufacturing Engineering and Technology. London: Springer 2013; 487-566. https://doi.org/10.1007/978-1-4471-4976-7_48-4
Teisanu C and Sima G. Solid state foaming in two steps sintering to produce HAP-based biocomposites for bone grafting. In: Rotaru A, Ed. Advanced Engineering Materials. Recent Developments for Medical, Technological and Industrial Applications. Rostock: Academica Greifswald Publishing House 2016; 43-86.
Gingu O, Cojocaru D, Ristoscu CG, Sima G, Teisanu C and Mangra M. The influence of the foaming agent on the mechanical properties of the PM hydroxyapatite-based biocomposites processed by two-step sintering route. Journal of Optoelectronics and Advanced Materials 2015; 17(7-8): 1044-49.
Marinescu C, Sofronia A, Anghel EM, Baies R, Constantin D, Seciu AM, et al. Microstructure, stability and biocompatibility of hydroxyapatite-titania nanocomposites formed by two-step sintering process. Arabian Journal of Chemistry 2017; available online: https://doi.org/10.1016/j.arabjc.2017.01.019 https://doi.org/10.1016/j.arabjc.2017.01.019
Pascu CI, Gingu O, Ciupitu I and Rotaru P. Biocomposite material and its elaboration process. Romanian Patent 125714. 2015.
Burstein FD. State of the art: Bone substitutes. Cleft Palate Craniofac J 2000; 37: 1-3 https://doi.org/10.1597/1545- 1569(2000)037<0001:ESNTIT>2.3.CO;2
Schnettler R, Stahl JP, Alt V, Pavlidis T, Dingeldein E and Wenisch S. Calcium phosphate-based bone substitutes. Eur J Trauma 2004; 30(4): 219-29. https://doi.org/10.1007/s00068-004-1393-x
Mour M, Das D, Winkler T, Hoenig E, Mielke G, Morlock MM, et al. Advances in porous biomaterials for dental and orthopaedic applications. Materials 2010; 3(5): 2947-74 https://doi.org/10.3390/ma3052947
Dobos P. Synthesis of foamed bioceramics for potential medical applications, M. Ph.D. Thesis, Brno University of Technology, Faculty of Chemistry (2011).
Liu H, He P, Feng JC and Cao J. Kinetic study on nonisothermal dehydrogenation of TiH2 powders. Int J Hydrogen Energy 2009; 34: 3018-25. https://doi.org/10.1016/j.ijhydene.2009.01.095
Blowing agents. Available from: http://www.icodassociates. com/docs/blowing_agents.pdf
Kevorkijan V. Low cost aluminium foams made by CaCO3 particulates. Metall and Mat Eng 2015; 16(3): 205-19.
Halikia I, Zoumpoulakis L, Christodoulou E and Prattis D. Kinetic study of the thermal decomposition of calcium carbonate by isothermal methods of analysis. EJMP and EP 2001; 1(2): 89 -102.
Haeshche M, Lehmhus D, Weise JA, Wichmann M and Magnabosco Mocellin IC. Carbonates as foaming agent in chip-based aluminium foam precursor. J Mater Science and Technology 2010; 26: 845-50. https://doi.org/10.1016/S1005-0302(10)60135-1
Li SH, De Wijn JR, Layrolle P and De Groot K. Synthesis of macroporous hydroxyapatite scaffolds for bone tissue engineering. J Biomed Mater Res 2002; 61: 109-120. https://doi.org/10.1002/jbm.10163
Ishiwata K, Tawara K and Matsushita J. Characterization of Hydroxyapatite Containing of Titanium Hydride Sintered Body by Nano Size Powder, Materials Science Forum 2013; 761: 135-139. https://doi.org/10.4028/www.scientific.net/MSF.761.135
Montufar EB, Gil C, Traykova T, Ginebra MP and Planell J. Foamed beta-tricalcium phosphate scaffolds, Key Eng Mater 2008; 361-363: 323-6. https://doi.org/10.4028/www.scientific.net/KEM.361-363.323
Feng P, Niu M, Gao C, Peng S and Shuai C. A novel twostep sintering for nano-hydroxyapatite scaffolds for bone tissue engineering 2014; Sci Rep; 4; 5599. https://doi.org/10.1038/srep05599
Farzin A, Ahmadian M and Fathi MH. Comparative evaluation of biocompatibility of dense nanostructured and microstructured hydroxyapatite/titania composites, Mat Sci and Eng C 2013: 2251-2257. https://doi.org/10.1016/j.msec.2013.01.053
Gingu O, Pascu CI, Lupu N and Benga GC. Material biocompozit si procedeu de elaborare a acestuia, Romanian patent, 125713/2015 - O.S.I.M. Romania.
Rudenko N and Laptev A. Compaction and properties of highly porous powder parts produced with various pore formers. Mechanical Testing and Diagnosis 2001; 1: 82-87.